American women have been on fire, and they’ll be turning up the heat in the 2025 US Open women’s singles main draw, which was revealed on Thursday.
Top 10 seeds Coco Gauff (No. 3), Madison Keys (No. 6) and Amanda Anisimova (No. 8) are keeping the bottom half warm, while compatriots Jessica Pegula (No. 4) and Emma Navarro (No. 10) join defending US Open champion Aryna Sabalenka in the top half.
Based on how this year’s Grand Slam finals have played out thus far—with no repeat titlists yet this year—it could be anyone’s game. But one trend has remained consistent: An American woman has competed in the past four consecutive Grand Slam finals.
Keys launched into 2025 with an Australian Open victory over Sabalenka, and Gauff stopped Sabalenka in the Roland Garros final. Now, as Sabalenka looks to defend her US Open title and succeed in her last chance at a 2025 Grand Slam singles title, many wonder if an American woman will meet her in yet another big-stage final.
But that's not the only big storyline to be found in the full bracket. Read on for more top takeaways from the 2025 US Open women’s singles draw.
Sabalenka and Pegula could meet early in the semifinals
Last year, Sabalenka overcame Pegula to win her first US Open singles title, making her the first woman to claim both hard-court majors in a single season since 2016. The two could play a round earlier in New York this year, as No. 1 seed Sabalenka and Pegula both landed in the draw’s top half.
However, their path to reunion is a tricky one. Sabalenka will open against Switzerland's Rebeka Masarova, while Pegula starts off against Egyptian Mayar Sherif. Sabalenka's first seeded match-up could come in the third round against No. 31 Leylah Fernandez. Similarly, Pegula could meet No. 30 Dayana Yastremska in the third round. On the way to a potential semifinal, Sabalenka could also face recent Cincinnati runner-up and No. 7 seed Jasmine Paolini; and Pegula could meet up with Mirra Andreeva in the quarterfinals, who has made it through to quarters in both Wimbledon and Roland Garros this year.
Gauff vies for second US Open title
The 2023 US Open champion will be on a hunt to reclaim the title here. She started off this year strong, with a quarterfinal run at the Australian Open, followed by her Roland Garros championship. She'll begin her 2025 campaign in Flushing with a first-round matchup with Australian Ajla Tomljanovic, who defeated 23-time Grand Slam singles champion Serena Williams here in the American's final career match in 2022. Gauff also enters the tournament with a new coach, biomechanics specialist Gavin MacMillan, after parting ways with Matthew Daly just days before the tournament and figures to come here especially determined, given her first-round exit at Wimbledon. Her best showing this summer has been a run to the quarters at Cincinnati.
Venus Williams makes her US Open return amid a stellar American field
After a hiatus last year, the Queen of Queens is returning to Flushing Meadows, in her first Grand Slam singles appearance since the 2023 US Open. Venus Williams is no stranger to the USTA Billie Jean King National Tennis Center, playing in 24 of the past 27 US Open tournaments, and taking the women’s singles crown in 2000 and 2001.
She’s already gotten some practice on the blue courts, having competed in the 2025 US Open Mixed Doubles Championship with Reilly Opelka. A singles advance will take some doing, as having entered the tournament as a wild card, Williams will face No. 11 seed Karolina Muchova in the first round.
Rising star Victoria Mboko makes her US Open main draw debut
If you haven’t heard of Victoria Mboko, you will. The rising phenom claimed her first WTA title in Montreal earlier this month, becoming the third Canadian to win her home nation’s biggest tournament—and fought her way through four former Grand Slam champions to get there. While she began the season at No. 333, her Montreal victory helped launch her to career high of No. 24, propelling her into her first US Open singles main draw appearance. Seeded at No. 22, Mboko will first face Czechia’s Barbora Krejcikova.
Can Swiatek keep the energy going?
Swiatek’s had a busy week. Fresh off her singles final victory at the Cincinnati Open on Monday, the world No. 2 beelined to New York for the 2025 US Open Mixed Doubles Championship—where she and partner Casper Ruud finished as runners-up. The Pole notched her sixth Grand Slam title at Wimbledon in July, and also made semifinal appearances at the Australian Open and Roland Garros.
She’ll start off her 2025 US Open title run against Colombian Emiliana Arango, and could face Anisimova—who she bested in the Wimbledon final—in the quarterfinals.
